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Amphetamine is thought to inhibit monoamine oxidase, whereas the ability of amphetamine and its metabolites to inhibit different P450 isozymes and also other enzymes hasn't been adequately elucidated. In vitro experiments with human microsomes suggest minimal inhibition of CYP2D6 by amphetamine and insignificant inhibition of CYP1A2, 2D6, and 3A4 b